Tehran University of Medical Sciences (TUMS) Academic Journal of Surgery 2423-3218 4 2 2017 10 09 61 63 Zohreh Kazemi Department of Gynecologic Oncology, School of Medicine AND Research Development Unit Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Khadijeh Rezaie-Kahkhayi Department of Gynecologic Oncology, School of Medicine AND Amir Al-Momenin Hospital, Zabol University of Medical Sciences, Zabol, Iran Zahra Anfasi Gynecologist, Atieh Hospital, Tehran, Iran 2017 10 09 Background: Placenta percreta is a rare complication of pregnancy with catastrophic outcomes for both mother and fetus. Abnormal placental attachment due to inadequate deciduas formation between trophoblast and myometrium is the main histological finding. Case Report: We present a case of placenta percreta in a 25-year-old woman accompanied by spontaneous uterine rupture at 25th week of gestation. In view of clinical symptoms and laboratory findings, the patient underwent laparotomy with a primary diagnosis of acute abdomen. We found no predisposing factor for abnormal placentation. As our patient wished to remain fertile, a successful uterine repair was performed. Conclusions: Histological assessment of the uterus showed placenta percreta. It is very rare for placenta percreta to cause uterine rupture in the second trimester, especially in a patient without any risk factors. https://ajs.tums.ac.ir/index.php/ajs/article/view/123 https://ajs.tums.ac.ir/index.php/ajs/article/download/123/68