Tehran University of Medical Sciences (TUMS) Academic Journal of Surgery 2423-3218 6 1 2023 12 10 34 37 nima mohammadiafrakoti anesthesia fellowship seyyed mojtaba marashi professor of anesthesia shabnam saeidi professor of anesthesia mohammadsadegh talebikahdouei medical student fatemeh aghaei medical student 2023 08 05 Background: The objective of this study was to investigate the relationship between the increase in color Doppler ultrasound indices of the ophthalmic artery and the serum lactate level and the severity of the disease in patients with sepsis. Methods: This was a cross-sectional study conducted on 24 patients diagnosed with sepsis, who were admitted to the intensive care unit of Shariati Hospital. The patients were more than 18 years old, hospitalized in the first 42 hours, and selected by the portable color Doppler ultrasound available in the ICU department. The ESI probe was placed on the patient’s eye with the eyelid closed, and the ophthalmic artery was located. The indices including RI, PSV, PI were measured along with their serum lactate levels. The correlation of these indices with the severity of sepsis was checked. Results: In this study, 24 patients who were less than 81 years old were diagnosed with sepsis and had a sofa score above 3. It was observed that there is a significant relationship between the dose of increased lactate levels and PSV1, and this parameter can be considered a predictive factor. It was also observed that there is a significantrelationship between the dose of increased lactate levels and PSV2, and this parameter can be considered as am predictive factor. Additionally, there is a significant relationship between the dose of increased levels of lactateand PI, and this parameter can be considered as a predictive factor. Conclusions: The study found a significant relationship between increased levels of lactate and decreased bloodsupply in the optic artery. It is suggested that due to the lack of numbers in this study, more samples should be investigated in future studies. In a scientific article, the use of “we” and “our” should be avoided. If necessary, the third person should be used. https://ajs.tums.ac.ir/index.php/ajs/article/view/238 https://ajs.tums.ac.ir/index.php/ajs/article/download/238/113