Tehran University of Medical Sciences (TUMS) Academic Journal of Surgery 2423-3218 7 4 2025 01 04 113 118 Parinaz Sedadi Tehran univercity of medical science Ali Ashraf 0000-0002-7437-879X Ali Pourramazni 0000-0002-1399-1670 Roghaye Zareh 0000-0003-0971-2832 2024 09 26 Background: Post-traumatic stress disorder (PTSD) is a psychological disorder resulting from a previous traumatic experience. The objective of the present study was to investigate the prevalence of PTSD and its related risk factors among Intensive Care Unit (ICU) survivors. Methods: A total of 152 patients were followed up prospectively for one month. All included participants had Glasgow Coma Scale scores ranging from 12 to 15. PTSD was assessed using a Persian-translated version of the PTSD Checklist (PCL). Data were analyzed using SPSS 22.0 software. Results: Among the participants, seventy-two (47.4%) men and eighty (52.6%) women with a mean age of 54.5 ± 19.19 years responded to the questionnaire. The prevalence of post-discharge PTSD was 87.5%. There was a significant correlation between PTSD mean score and clinical factors such as hospitalization reason, self and familial history of psychological disorders, and Richmond Agitation Sedation Score (RASS) (p < 0.05). Conclusions: Our findings suggest that, despite often being ignored, post-discharge PTSD is a significant psychological issue for ICU survivors. This highlights the importance of supportive care plans for patients with a history of mental disorders and agitation. The involvement of psychotherapists is crucial to improving postdischarge quality of life. https://ajs.tums.ac.ir/index.php/ajs/article/view/279