Original Article

Comparative Study of Quality of Life After Surgery in Sigmoid and Rectal Cancers: A Single-Center Prospective Study

Abstract

Background: Sigmoid and rectal cancers are common malignancies that necessitate surgical resection as the
primary treatment modality. However, surgery can significantly impact the quality of life (QoL) of patients,
particularly in terms of bowel function, sexual function, and psychological well-being. This study aimed to
compare the QoL of patients who underwent surgery for sigmoid and rectal cancers.
Methods: A prospective study was conducted on 90 patients who underwent elective surgery for sigmoid or rectalcancer between January 2019 and December 2021 at the center. The QLQ-C30 and QLQ-CR29 questionnaireswere utilized to assess the QoL of patients post-surgery. The QoL scores between the two groups were compared using t-tests and repeated measures ANOVA.
Results: The average age of the patients was years, and 57.8% were females. The sigmoid group comprised
44 patients (48.8%) who underwent sigmoid colectomy, and the rectal group consisted of 46 patients (51.2%)
who underwent low anterior resection. There were no significant differences in the baseline characteristics and
QLQ-C30 scores between the two groups and also in other categories (sex, age groups, and cancer stages) (p >
0.05). However, a significant difference was observed between the QLQ-CR29 scores of the two surgical groups
(p < 0.05). QLQ-CR29 was not significantly different between sex and age groups and cancer stages (p > 0.05).
Conclusions: The study demonstrated that surgery for sigmoid and rectal cancers deteriorated the QoL of
patients, irrespective of the type of surgery or the location of the tumor. There was no significant difference in the QoL between the sigmoid and rectal groups measured by QLQ-C30. However, QLQ-CR29 showed significantlybetter QoL for the rectal group.

 

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IssueVol 6 No 1 (2023) QRcode
SectionOriginal Article(s)
DOI https://doi.org/10.18502/ajs.v6i1.14715
Keywords
Quality of life, proctocolectomy, low anterior resection, sigmoid cancer, rectal cancer Quality of life proctocolectomy low anterior resection sigmoid cancer rectal cancer
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How to Cite
1.
ahmadi Tafti seyed mohsen, Elyasi A, Najafi MS, Kazemeini A, Meshkati Yazd SM, Dashtkuhi M, Behboudi B, Fazeli MS, Keshvari A, Keramati MR. Comparative Study of Quality of Life After Surgery in Sigmoid and Rectal Cancers: A Single-Center Prospective Study. AJS. 2023;6(1):29-33.