Academic Journal of Surgery 2017. 4(3):82-86.

Pancreas Transplantation: A Review of Literature
Maria Ajdari, Reza Saidi, Mehdi Jafari, Abolfazl Shojaiefard, Shirzad Nasiri, Ali Mir, Ahmadreza Soroush

Abstract


Pancreas transplantation has emerged as an effective treatment for patients with diabetes mellitus, especially those with established end-stage renal disease. Surgical and immunosuppressive advances have significantly improved allograft survival. The procedure reduces mortality compared with diabetic kidney transplant recipients and waitlisted patients. Improvements in diabetic nephropathy and retinopathy have also been demonstrated. Pancreas transplantation can improve cardiovascular risk profiles, improve cardiac function, and decrease cardiovascular events. Finally, improvements in diabetic neuropathy and quality of life can result from pancreas transplantation. Pancreas transplantation remains the most effective method to establish durable euglycemia for patients with diabetes mellitus.


Keywords


Pancreas transplantation; Pancreas; Kidney; Transplantation; Diabetes mellitus; Islet transplantation

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