Original Article

Investigation of Biocompatible Wound Dressing and Skin Graft Treatment Methods in the Healing of Skin Wounds of 3rd Degree Burn Trauma in Motahari Hospital: A Clinical Trial

Investigation of biocompatible wound dressing and skin graft treatment methods in the healing of skin wounds

Abstract

Background: One of the primary concerns among burn patients with third-degree skin injuries is the healing
process and the severity of resulting skin lesions—an issue that has attracted considerable research attention.
Accordingly, the present study aimed to evaluate the therapeutic effects of biocompatible wound dressings and
skin grafting on the healing of third-degree traumatic burn wounds in patients admitted to Motahari Hospital.
Methods: This semi-experimental randomized clinical trial was conducted in 2024. The study population
included 18 patients with third-degree traumatic burns covering less than 5 cm², referred to the Motahari Burn
Center in Tehran. Data were collected using a researcher-designed form. Statistical analyses were performed
using SPSS software, employing the Mann–Whitney and Spearman tests.
Results: The mean age of participants was 36.25 years, and most were male (77.77%). The leading cause of burns was gas exposure (44.43%), and 66.68% of patients had burns covering 25% to 45% of total body surface area.
Patients treated with biocompatible wound dressings experienced significantly less scar formation, improved
follicle and dermal appendage restoration, and more aesthetically favorable skin regeneration.
Conclusions: Addressing patients' concerns about wound healing is essential, and effective therapeutic
approaches should be employed. Based on the study's findings, the use of biocompatible wound dressings is
recommended in skin and burn recovery services.

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IssueVol 8 No 2 (2025) QRcode
SectionOriginal Article(s)
Keywords
Biocompatible Wound Dressing Skin Graft Burn Injury Skin Repair Trauma
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1.
Mohammadi Mazleghani K, Rezaei Tavirani M, Nagehi A, Dahmardehei M, Rezaei Tavirani M. Investigation of Biocompatible Wound Dressing and Skin Graft Treatment Methods in the Healing of Skin Wounds of 3rd Degree Burn Trauma in Motahari Hospital: A Clinical Trial. AJS. 2025;8(2):70-74.